Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.50 |
| ▸ | NPY1R | P25929 | 8/20 | 0.50 |
| ▸ | NPY2R | P49146 | 6/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.50 |
| ▸ | GLP1R | P43220 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | GIPR | P48546 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.46 |
| ▸ | FNTB | P49356 | 4/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.46 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816881 | 0.95 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29816609 | 0.94 | NPY4R (0.59) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29816829 | 0.93 | GLP1R (0.50) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29816694 | 0.91 | GLP1R (0.57) | GLP1RGCGRGIPRIL23R | |
| SCHEMBL31596266 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RIL23R | |
| SCHEMBL29462004 | 0.87 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL30613908 | 0.86 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL38660333 | 0.86 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL29799693 | 0.85 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29540161 | 0.84 | NPY4R (0.66) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051784-A1 | MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-02-13 | — | — | US | disclosed |
| US-12163134-B2 | Modified aminoacyl-tRNA synthetase and use thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-12-10 | — | — | US | disclosed |
| EP-4166664-A1 | MODIFIED AMINOACYL-TRNA SYNTHETASE AND USE THEREOF | Chugai Seiyaku Kabushiki Kaisha (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-3269809-B1 | MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2022-07-27 | — | — | EP | disclosed |