Sugi Predict

Sugi Predict / Compounds / SCHEMBL29816609

SCHEMBL29816609

SCHEMBL29816609

CSCC[C@H](NC=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 18/20 0.59
▸ NPY1R P25929 11/20 0.59
▸ NPY5R Q15761 10/20 0.59
▸ NPY2R P49146 7/20 0.59
▸ GLP1R P43220 1/20 0.50
▸ GCGR P47871 1/20 0.50
▸ GIPR P48546 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29816488 0.94 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2RGLP1R
SCHEMBL29816881 0.93 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RGLP1R
SCHEMBL29816829 0.93 GLP1R (0.50) NPY4RNPY1RNPY5RNPY2RGLP1R
SCHEMBL29816694 0.86 GLP1R (0.57) GLP1RGCGRGIPR
SCHEMBL30497933 0.85 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30497932 0.85 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30497928 0.85 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16976098 0.85 GLP1R (0.58) NPY4RNPY1RNPY5RNPY2RGLP1R
SCHEMBL29799693 0.85 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RGLP1R
SCHEMBL30613908 0.85 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051784-A1 MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-02-13 — — US disclosed
US-12163134-B2 Modified aminoacyl-tRNA synthetase and use thereof CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-10 — — US disclosed
EP-4166664-A1 MODIFIED AMINOACYL-TRNA SYNTHETASE AND USE THEREOF Chugai Seiyaku Kabushiki Kaisha (JP) 2023-04-19 — — EP disclosed
EP-3269809-B1 MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF CHUGAI PHARMACEUTICAL CO LTD (JP) 2022-07-27 — — EP disclosed
Send feedback