SCHEMBL29816829

SCHEMBL29816829

CSCC[C@H](NC=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 1/20 0.50
▸ GCGR P47871 1/20 0.50
▸ GIPR P48546 1/20 0.50
▸ NPY4R P50391 9/20 0.49
▸ NPY1R P25929 6/20 0.49
▸ NPY2R P49146 4/20 0.49
▸ NPY5R Q15761 4/20 0.49
▸ IL23R Q5VWK5 3/20 0.48
▸ FNTA P49354 2/20 0.47
▸ FNTB P49356 2/20 0.47
▸ TFPI P10646 1/20 0.47
▸ BCL2L1 Q07817 1/20 0.46
▸ BAD Q92934 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29816488 0.93 NPY4R (0.50) GLP1RGCGRGIPRNPY4RNPY1R
SCHEMBL29816609 0.93 NPY4R (0.59) GLP1RGCGRGIPRNPY4RNPY1R
SCHEMBL29816881 0.93 NPY4R (0.49) GLP1RGCGRGIPRNPY4RNPY1R
SCHEMBL29611531 0.88 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL18613835 0.88 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL18613838 0.88 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL10428706 0.88 IL23R (0.54) GLP1RGCGRGIPRNPY4RNPY1R
SCHEMBL10428709 0.88 IL23R (0.54) GLP1RGCGRGIPRNPY4RNPY1R
SCHEMBL29816823 0.87 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL29512422 0.86 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051784-A1 MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-02-13 — — US disclosed
US-12163134-B2 Modified aminoacyl-tRNA synthetase and use thereof CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-10 — — US disclosed
EP-4166664-A1 MODIFIED AMINOACYL-TRNA SYNTHETASE AND USE THEREOF Chugai Seiyaku Kabushiki Kaisha (JP) 2023-04-19 — — EP disclosed
EP-3269809-B1 MODIFIED AMINOACYL-tRNA SYNTHETASE AND USE THEREOF CHUGAI PHARMACEUTICAL CO LTD (JP) 2022-07-27 — — EP disclosed
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