Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.55 |
| ▸ | CHKA | P35790 | 5/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16121663 | 0.95 | CHKA (0.62) | PARP1CHEK1PARP2PARP3CHKA | |
| SCHEMBL29537476 | 0.86 | MEN1 (0.50) | PARP1BCAT2GRM2PPARG | |
| SCHEMBL31717616 | 0.84 | PARP1 (0.59) | PARP1PARP2PARP3BCAT2GRM2 | |
| SCHEMBL17465322 | 0.84 | CHKA (0.64) | CHKAMC4RITGB1ITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL31717432 | 0.83 | PARP1 (0.58) | PARP1PARP2PARP3BCAT2GRM2 | |
| SCHEMBL30108265 | 0.80 | PARP1 (0.58) | PARP1CHEK1PARP2PARP3CHKA | |
| SCHEMBL28684963 | 0.80 | PARP1 (0.58) | PARP1CHEK1PARP2PARP3CHKA | |
| SCHEMBL17729936 | 0.80 | BCAT2 (0.59) | PARP1CHEK1PARP2PARP3BCAT2 | |
| SCHEMBL2925004 | 0.79 | PARP1 (0.48) | PARP1CHEK1PARP2PARP3ITGB1 | |
| SCHEMBL6184315 | 0.78 | NR1H2 (0.56) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |