Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787868 | 1.00 | TAAR1 (1.00) | TAAR1ESR2CYP3A4TDP1HSD17B10 | |
| SCHEMBL23704123 | 0.86 | TAAR1 (0.76) | TAAR1ESR2CYP3A4TDP1HSD17B10 | |
| SCHEMBL3790609 | 0.84 | TAAR1 (0.72) | TAAR1ESR2CYP3A4MAP4K4MAOA | |
| SCHEMBL15605009 | 0.83 | TAAR1 (0.71) | TAAR1ESR2CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL777750 | 0.83 | TAAR1 (0.71) | TAAR1ESR2CYP3A4MAP4K4CYP17A1 | |
| SCHEMBL309757 | 0.83 | TAAR1 (0.70) | TAAR1CYP3A4TDP1HSD17B10MAP4K4 | |
| SCHEMBL14309787 | 0.83 | TAAR1 (0.70) | TAAR1CYP3A4TDP1HSD17B10MAP4K4 | |
| SCHEMBL14302425 | 0.83 | TAAR1 (0.70) | TAAR1CYP3A4TDP1HSD17B10MAP4K4 | |
| SCHEMBL198702 | 0.83 | TAAR1 (0.68) | TAAR1ESR2CYP3A4MAP4K4CYP17A1 | |
| SCHEMBL28716071 | 0.82 | TAAR1 (0.68) | TAAR1ESR2CYP3A4TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |