Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791036 | 0.87 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL3684019 | 0.87 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL3689576 | 0.87 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL3682415 | 0.87 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL3680794 | 0.87 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL31757029 | 0.80 | PARP1 (0.53) | PARP2PARP1HTR1ASCN1ASCN2A | |
| SCHEMBL363916 | 0.80 | PARP1 (0.53) | PARP2PARP1HTR1ASCN1ASCN2A | |
| SCHEMBL3290607 | 0.75 | METAP2 (0.42) | HSD11B1 | |
| SCHEMBL2218013 | 0.74 | CHRNA7 (0.50) | — | |
| SCHEMBL21590329 | 0.74 | PARP1 (0.49) | PARP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |