Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | MSN | P26038 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791036 | 1.00 | METAP2 (0.42) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3680794 | 1.00 | METAP2 (0.42) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3689576 | 1.00 | METAP2 (0.42) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3682415 | 1.00 | METAP2 (0.42) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29818375 | 0.87 | PARP2 (0.43) | HSD11B1 | |
| SCHEMBL3290607 | 0.87 | METAP2 (0.42) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3705935 | 0.81 | SLC6A3 (0.43) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30646221 | 0.80 | KDM4E (0.47) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1116597 | 0.77 | KDM4E (0.44) | METAP2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8628022 | 0.77 | KDM4E (0.44) | METAP2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129223-B1 | FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE DERIVATIVE, CYPRODINIL AND AN UNSATURATED FATTY ACID | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-14 | — | — | EP | disclosed |
| US-20130178491-A1 | FUNGICIDAL COMPOSITION | SYNGENTA CROP PROTECTION, LLC (US) | 2013-07-11 | — | — | US | disclosed |
| US-20100113552-A1 | FUNGICIDAL COMPOSITION | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| EP-2129223-A2 | FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE DERIVATIVE, CYPRODINIL AND AN UNSATURATED FATTY ACID | Syngeta Participations AG (CH) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008119439-A2 | FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE DERIVATIVE, CYPRODINIL AND AN UNSATURATED FATTY ACID | SYNGENTA PARTICIPATIONS AG (CH) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113552-A1 | FUNGICIDAL COMPOSITION | CYCS, CYP1A2, CYP1A1 | METAP2 1599/4885KDM4E 3176/4885ALDH1A1 945/4885 |
| US-20130178491-A1 | FUNGICIDAL COMPOSITION | CYP1A2, CYCS, FFAR3 | METAP2 1492/4885KDM4E 3261/4885ALDH1A1 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.