Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 8/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26815954 | 1.00 | CFD (0.33) | CFDDRD2MEN1ALDH1A1GAA | |
| SCHEMBL27374232 | 1.00 | CFD (0.33) | CFDDRD2MEN1ALDH1A1GAA | |
| SCHEMBL24666023 | 0.93 | DRD2 (0.33) | DRD2 | |
| SCHEMBL29820410 | 0.87 | CFD (0.35) | CFD | |
| SCHEMBL26816158 | 0.87 | CFD (0.35) | CFD | |
| SCHEMBL30341445 | 0.85 | CFD (0.35) | CFDMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL29820457 | 0.85 | CFD (0.35) | CFDMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL26816045 | 0.85 | CFD (0.35) | CFDMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL29230659 | 0.84 | CFD (0.35) | CFDDRD2 | |
| SCHEMBL24665821 | 0.84 | CFD (0.35) | CFDDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308095-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022198196-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |