Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201552 | 0.90 | CYP19A1 (0.80) | CYP19A1IDO1TDO2CCR1CCR2 | |
| SCHEMBL4564456 | 0.82 | CYP19A1 (0.69) | CYP19A1IDO1TDO2TSHRALDH1A1 | |
| SCHEMBL29820095 | 0.82 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2NOTUMIDO1 | |
| SCHEMBL10194241 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2NOTUMIDO1 | |
| SCHEMBL16129814 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2HTR1A | |
| SCHEMBL6881194 | 0.81 | CYP19A1 (0.67) | CYP19A1IDO1TDO2CCR1CCR2 | |
| SCHEMBL3153071 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2LMNAMAPT | |
| SCHEMBL17288294 | 0.80 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2IDO1TDO2 | |
| SCHEMBL31286284 | 0.80 | CYP19A1 (0.61) | CYP19A1NOTUMCCR1CCR2CCR4 | |
| SCHEMBL155247 | 0.80 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2MAPTCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119101052-A | Matrine-triazole derivative and synthesis method thereof | 吉林医药学院 | 2024-12-10 | — | — | CN | disclosed |
| CN-114957222-B | Compound and preparation method and application thereof | 内蒙古民族大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-114957222-A | Compound and preparation method and application thereof | 内蒙古民族大学 | 2022-08-30 | — | — | CN | disclosed |