⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577578 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL15667907 | 0.77 | — | — | |
| SCHEMBL5713387 | 0.77 | NOS1 (0.33) | — | |
| SCHEMBL27958769 | 0.72 | — | — | |
| SCHEMBL27947041 | 0.72 | — | — | |
| SCHEMBL27709108 | 0.72 | — | — | |
| SCHEMBL596295 | 0.72 | — | — | |
| SCHEMBL6008568 | 0.72 | — | — | |
| SCHEMBL13558399 | 0.72 | — | — | |
| SCHEMBL8833055 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454246-A | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-107074771-B | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-03-20 | — | — | CN | claimed |
| US-20140336208-A1 | 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-13 | — | — | US | claimed |
| US-8815881-B2 | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-08-26 | — | — | US | claimed |
| CN-103068806-A | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | SIENA BIOTECH SPA | 2013-04-24 | — | — | CN | claimed |
| US-20120035195-A1 | 1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS | SIENA BIOTECH S.P.A., AN ITALIAN COMPANY (IT) | 2012-02-09 | — | — | US | claimed |
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | claimed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | claimed |
| US-4788205-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1988-11-29 | — | — | US | claimed |
| US-20230159530-A1 | MORPHINAN DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| CN-111454246-A | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-107074771-B | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-105431418-B | Metalloenzyme Inhibitor Compounds | 北卡罗来纳维亚梅特制药公司 | 2019-02-05 | — | — | CN | disclosed |
| US-20180340138-A1 | ENZYME STABILIZERS | HENKEL AG & CO. KGAA (DE) | 2018-11-29 | — | — | US | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |
| CN-1075143-A | Optically active azole compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-08-11 | — | — | CN | disclosed |
| CN-1072680-A | Optically active azole compounds and method for making thereof and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-06-02 | — | — | CN | disclosed |
| US-4788205-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4402727-A | Substituted azolylalkyl phenoxyphenoxyalkane-carboxylates as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |