⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713387 | 0.77 | NOS1 (0.33) | — | |
| SCHEMBL27947041 | 0.72 | — | — | |
| SCHEMBL27709108 | 0.72 | — | — | |
| SCHEMBL126472 | 0.72 | — | — | |
| SCHEMBL298218 | 0.72 | — | — | |
| SCHEMBL596295 | 0.72 | — | — | |
| SCHEMBL13558399 | 0.72 | — | — | |
| SCHEMBL27958769 | 0.72 | — | — | |
| SCHEMBL8833055 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28755168 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106179767-A | A kind of application of 1,3,4 diazole 2 thiones flotation collectors | 中南大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-105884693-A | Parasiticidal Compositions Comprising Benzimidazole Derivatives, Methods And Uses Thereof | 梅里亚有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102511216-A | Ridging method for greenhouse cucumber cultivation without continuous cropping obstacles | UNIV CHINA AGRICULTURAL | 2012-06-27 | — | — | CN | disclosed |
| CN-1315834-C | 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines | PROCTER & GAMBLE (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1878772-A | Bicyclic pyrazolone cytokine inhibitors | PROCTER & GAMBLE (US) | 2006-12-13 | — | — | CN | disclosed |
| CN-1249066-C | 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines | PROCTER & GAMBLE (US) | 2006-04-05 | — | — | CN | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| CN-1681819-A | 6, 7-dihydro-5H-pyrazolo [1, 2-a ] pyrazol-1-ones which control inflammatory cytokines | PROCTER & GAMBLE (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1556811-A | 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines | — | 2004-12-22 | — | — | CN | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |