Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAPGEF3 | O95398 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822000 | 0.94 | MAPT (0.43) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821753 | 0.93 | ALOX12 (0.44) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29822193 | 0.92 | MEN1 (0.52) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821844 | 0.89 | MEN1 (0.37) | ALOX12MEN1KMT2ATHRBMAPT | |
| SCHEMBL29821830 | 0.87 | ALOX12 (0.41) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821504 | 0.87 | MEN1 (0.52) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821725 | 0.87 | MEN1 (0.40) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821950 | 0.86 | MEN1 (0.51) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821628 | 0.86 | MEN1 (0.39) | ALOX12MEN1KMT2ARAPGEF3THRB | |
| SCHEMBL29821836 | 0.86 | THRB (0.57) | ALOX12MEN1KMT2ARAPGEF3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4036090-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-08-03 | — | — | EP | disclosed |