Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.57 |
| ▸ | CA2 | P00918 | 10/20 | 0.57 |
| ▸ | CA9 | Q16790 | 8/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11143885 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL23132 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL30442 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL9745435 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL11212246 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL9745429 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL339361 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL344843 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL7532328 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| SCHEMBL88035 | 0.98 | CA1 (0.59) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116646682-A | Diaphragm and preparation method and application thereof | 惠州锂威电子科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116348086-A | Surfactant-containing formulations of ceramide | 西姆莱斯股份公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-4033246-A1 | A DEVICE, SYSTEM AND METHOD FOR CUSTOMISING A PERSONAL CARE PRODUCT | Clarity Lab Limited (IE) | 2022-07-27 | — | — | EP | disclosed |