Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823437 | 1.00 | CCR1 (0.42) | CCR1KCNH2KMT2AMEN1LMNA | |
| SCHEMBL1879075 | 1.00 | CCR1 (0.42) | CCR1KCNH2KMT2AMEN1LMNA | |
| SCHEMBL29823495 | 0.87 | CCR3 (0.45) | KMT2AMEN1ALDH1A1CCR3 | |
| SCHEMBL1870607 | 0.87 | CCR3 (0.45) | KMT2AMEN1ALDH1A1CCR3 | |
| SCHEMBL5790256 | 0.80 | KMT2A (0.41) | KMT2AMEN1LMNAALDH1A1CCR3 | |
| SCHEMBL28433679 | 0.78 | PKM (0.45) | — | |
| SCHEMBL29823478 | 0.78 | PKM (0.45) | — | |
| SCHEMBL29823211 | 0.76 | KMT2A (0.50) | KMT2AMEN1ALDH1A1CCR3 | |
| SCHEMBL1873995 | 0.76 | KMT2A (0.50) | KMT2AMEN1ALDH1A1CCR3 | |
| SCHEMBL1872883 | 0.76 | MEN1 (0.41) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902411-A | Compositions and methods for expanding hematopoietic stem and progenitor cells and treating inherited metabolic disorders | 美真达治疗公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111683669-A | Compositions and methods for hematopoietic stem and progenitor cell transplantation therapy | 美真达治疗公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111542597-A | Compositions and methods for expanding hematopoietic stem and progenitor cells | 美真达治疗公司 | 2020-08-14 | — | — | CN | disclosed |