Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | BACE1 | P56817 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877188 | 1.00 | CXCR4 (0.49) | CXCR4SIGMAR1CYP3A4CYP2D6BCHE | |
| SCHEMBL1877208 | 0.92 | ALDH1A1 (0.43) | CXCR4SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL29823258 | 0.92 | ALDH1A1 (0.43) | CXCR4SIGMAR1BCHEACHEBACE1 | |
| SCHEMBL29823344 | 0.85 | CXCR4 (0.51) | CXCR4SIGMAR1CYP3A4BCHEACHE | |
| SCHEMBL1879660 | 0.85 | CXCR4 (0.51) | CXCR4SIGMAR1CYP3A4BCHEACHE | |
| SCHEMBL29823986 | 0.84 | MEN1 (0.41) | CXCR4SIGMAR1CYP3A4CYP2D6BCHE | |
| SCHEMBL1872883 | 0.84 | MEN1 (0.41) | CXCR4SIGMAR1CYP3A4CYP2D6BCHE | |
| SCHEMBL1871880 | 0.80 | CXCR4 (0.49) | CXCR4SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL1886813 | 0.80 | HRH3 (0.45) | CXCR4CYP3A4CYP2D6 | |
| SCHEMBL29823561 | 0.77 | SIGMAR1 (0.45) | CXCR4SIGMAR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308694-A1 | DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS | Magenta Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4143302-A1 | METHODS AND COMPOSITIONS FOR TRANSDUCING HEMATOPOIETIC STEM AND PROGENITOR CELLS IN VIVO | Magenta Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| WO-2022197776-A1 | DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS | Magenta Therapeutics, Inc. (US) | 2022-09-22 | — | — | WO | disclosed |
| EP-4051298-A1 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENTOR CELLS | Magenta Therapeutics, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |