SCHEMBL29823488

SCHEMBL29823488

CC(C)[C@H](NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)CCl

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FURIN P09958 15/20 0.59
CTSL P07711 1/20 0.55
PRSS1 P07477 2/20 0.54
PCSK6 P29122 1/20 0.54
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46
NPY4R P50391 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401358 0.85 CTSL (0.76) FURINCTSLPRSS1PCSK6
SCHEMBL30074409 0.85 CTSL (0.76) FURINCTSLPRSS1PCSK6
Thymocartin SCHEMBL29355849 0.82 NPY1R (0.50) FURINCTSLPRSS1PCSK6NPY1R
SCHEMBL29384677 0.80 FURIN (0.63) FURINCTSLPRSS1PCSK6NPY1R
SCHEMBL29349719 0.78 FURIN (0.60) FURINNPY1RNPY2RNPY4R
SCHEMBL6700441 0.78 GSR (0.45) FURINCTSLPCSK6
SCHEMBL6700436 0.78 GSR (0.45) FURINCTSLPCSK6
SCHEMBL31126783 0.78 DPP8 (0.46) FURINCTSLPCSK6NPY1RNPY2R
SCHEMBL31470824 0.77 CYP1A2 (0.56) NPY1RNPY2RNPY4R
SCHEMBL29394951 0.77 CYP1A2 (0.56) NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129370-A1 METHOD FOR REDUCING HEPATIC TRIGLYCERIDES ADAERATA, LIMITED PARTNERSHIP (CA) 2025-04-24 US disclosed
EP-4475854-A1 METHOD FOR REDUCING HEPATIC TRIGLYCERIDES Adaerata, Limited Partnership (CA) 2024-12-18 EP disclosed
WO-2023150869-A1 METHOD FOR REDUCING HEPATIC TRIGLYCERIDES ADAERATA, LIMITED PARTNERSHIP (CA) 2023-08-17 WO disclosed
US-20230149401-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS BP ASSET V, INC. (US) 2023-05-18 US disclosed
EP-4125897-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS BP Asset V, Inc. (US) 2023-02-08 EP disclosed
CN-115666567-A Furin inhibitors for the treatment of coronavirus infection BP资产V股份有限公司 2023-01-31 CN disclosed
WO-2022159787-A1 COMPOUNDS FOR THE TREATMENT OF A DISEASE OR DISORDER, METHODS FOR IDENTIFYING SAID COMPOUNDS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-07-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149401-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS FURIN, ACE, ACE2 FURIN 1/4885CTSL 18/4885PRSS1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.