Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878739 | 1.00 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1874025 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1881875 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30225577 | 0.78 | KMT2A (0.68) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14931741 | 0.78 | KMT2A (0.68) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14025550 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4428290 | 0.75 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1876917 | 0.74 | HPGD (0.40) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1874483 | 0.72 | CYP2D6 (0.39) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL22305532 | 0.72 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308694-A1 | DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS | Magenta Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-115997009-A | Methods and compositions for in vivo transduction of hematopoietic stem and progenitor cells | 美真达治疗公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4143302-A1 | METHODS AND COMPOSITIONS FOR TRANSDUCING HEMATOPOIETIC STEM AND PROGENITOR CELLS IN VIVO | Magenta Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| WO-2022197776-A1 | DOSING REGIMENS FOR HEMATOPOIETIC STEM CELL MOBILIZATION FOR STEM CELL TRANSPLANTS IN MULTIPLE MYELOMA PATIENTS | Magenta Therapeutics, Inc. (US) | 2022-09-22 | — | — | WO | disclosed |
| EP-4051298-A1 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENTOR CELLS | Magenta Therapeutics, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |