Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931741 | 1.00 | KMT2A (0.68) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL22305532 | 0.92 | ALDH1A1 (0.60) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL21975726 | 0.92 | KMT2A (0.60) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL30338458 | 0.92 | KMT2A (0.60) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL30338402 | 0.91 | KDM4E (0.66) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL5575878 | 0.91 | KDM4E (0.66) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL2947235 | 0.89 | ALDH1A1 (0.63) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL25376426 | 0.89 | ALDH1A1 (0.60) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL30967716 | 0.87 | L3MBTL1 (0.56) | KMT2AALDH1A1MEN1L3MBTL1KDM4E | |
| SCHEMBL3314110 | 0.86 | L3MBTL1 (0.62) | KMT2AALDH1A1MEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143302-A1 | METHODS AND COMPOSITIONS FOR TRANSDUCING HEMATOPOIETIC STEM AND PROGENITOR CELLS IN VIVO | Magenta Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |