Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243485 | 0.78 | LMNA (0.64) | LMNAALDH1A1MAPTHTTKMT2A | |
| SCHEMBL31308946 | 0.77 | LMNA (1.00) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL26623231 | 0.76 | KDM4E (0.60) | LMNAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL22450023 | 0.74 | MAPT (0.56) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL10596294 | 0.74 | LMNA (0.61) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL21503655 | 0.73 | KMT2A (0.55) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL21782109 | 0.72 | ESR1 (0.39) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL5243478 | 0.72 | LMNA (1.00) | LMNAALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL22535071 | 0.71 | RAB9A (0.59) | LMNAKMT2AMEN1 | |
| SCHEMBL27861126 | 0.71 | RAB9A (0.60) | LMNAALDH1A1MAPTKMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087486-A | Substituted bicyclic and tricyclic ureas and amides, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2022-09-20 | — | — | CN | disclosed |