SCHEMBL29829454

SCHEMBL29829454

CNC(=N)NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.53
▸ TLR2 O60603 2/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ CASP3 P42574 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14583977 1.00 MDM2 (0.53) MDM2TLR2KMT2AMDM4TP53
SCHEMBL12214738 1.00 MDM2 (0.53) MDM2TLR2KMT2AMDM4TP53
SCHEMBL12019008 0.92 TLR2 (0.49) MDM2TLR2KMT2A
SCHEMBL12040119 0.90 MDM2 (0.54) MDM2TLR2KMT2AMDM4TP53
SCHEMBL12214737 0.90 HDAC1 (0.53) MDM2TLR2KMT2A
SCHEMBL30285946 0.89 TLR2 (0.53) MDM2TLR2KMT2AMDM4TP53
SCHEMBL30302213 0.89 TLR2 (0.53) MDM2TLR2KMT2AMDM4TP53
SCHEMBL18148920 0.88 KMT2A (0.64) MDM2TLR2KMT2AMDM4TP53
SCHEMBL29401604 0.88 KMT2A (0.64) MDM2TLR2KMT2AMDM4TP53
SCHEMBL29423590 0.88 KMT2A (0.64) MDM2TLR2KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 MDM2 4693/4885TLR2 1235/4885KMT2A 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback