SCHEMBL29401604

SCHEMBL29401604

O=C(NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.64
MDM2 Q00987 6/20 0.56
MDM4 O15151 2/20 0.55
TP53 P04637 2/20 0.55
TLR2 O60603 2/20 0.54
CASP3 P42574 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18148920 1.00 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29423590 1.00 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119709 1.00 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119708 1.00 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29528567 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL260631 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL178733 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL178698 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401258 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29359997 0.97 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583900-B2 Peptide conjugates and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2026-03-24 US disclosed
US-20250367259-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE 2025-12-04 US disclosed
US-20250325683-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE SCRIPPS RESEARCH INST (US) 2025-10-23 US disclosed
US-20250320252-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE SCRIPPS RESEARCH INST (US) 2025-10-16 US disclosed
EP-4622673-A1 NOVEL CARRIERS FOR NUCLEIC ACID AND/OR PROTEIN DELIVERY Ludwig-Maximilians-Universität München (DE) 2025-10-01 EP disclosed
US-12337028-B2 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-06-24 US disclosed
US-12329823-B2 Long-acting dual GIP/GLP-1 peptide conjugates and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2025-06-17 US disclosed
WO-2024110492-A9 NOVEL CARRIERS FOR NUCLEIC ACID AND/OR PROTEIN DELIVERY LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2025-01-23 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE 2024-06-27 US disclosed
US-20230057847-A1 GLP2 RECEPTOR AGONISTS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2023-02-23 US disclosed
WO-2022257979-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE (US) 2022-12-15 WO disclosed
EP-4069726-A2 GLP2 RECEPTOR AGONISTS AND METHODS OF USE The Scripps Research Institute (US) 2022-10-12 EP disclosed
EP-4069275-A1 NEW MULTI-FUNCTIONAL OLIGOPEPTIDES EnliTISA (Shanghai) Pharmaceutical Co., Ltd. (CN) 2022-10-12 EP disclosed
EP-4069274-A1 PEPTIDE CONJUGATES AND METHODS OF USE The Scripps Research Institute (US) 2022-10-12 EP disclosed
CN-115052615-A Peptide conjugates and methods of use 斯克利普斯研究所 2022-09-13 CN disclosed
CN-115052886-A GLP2 receptor agonists and methods of use 斯克利普斯研究所 2022-09-13 CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114929259-A Novel multifunctional oligopeptides 艾缇亚(上海)制药有限公司 2022-08-19 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12337028-B2 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof SGMS1, SGMS2, PHOSPHO1 KMT2A 3238/4885MDM2 2400/4885MDM4 1392/4885
US-20230057847-A1 GLP2 RECEPTOR AGONISTS AND METHODS OF USE GLP1R, GIPR, GRPR KMT2A 3248/4885MDM2 3189/4885MDM4 4823/4885
US-12583900-B2 Peptide conjugates and methods of use GIPR, GLP1R, GCG KMT2A 1061/4885MDM2 4495/4885MDM4 4869/4885
US-20250325683-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE GLP1R, GIPR, GCGR KMT2A 2554/4885MDM2 4061/4885MDM4 4750/4885
US-20250367259-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF SGMS1, SGMS2, PHOSPHO1 KMT2A 3006/4885MDM2 2282/4885MDM4 1419/4885
US-12329823-B2 Long-acting dual GIP/GLP-1 peptide conjugates and methods of use GLP1R, GIPR, GCGR KMT2A 2554/4885MDM2 4061/4885MDM4 4750/4885
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF SGMS1, SGMS2, PHOSPHO1 KMT2A 3238/4885MDM2 2400/4885MDM4 1392/4885
US-20250320252-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE GLP1R, GIPR, GCGR KMT2A 2554/4885MDM2 4061/4885MDM4 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.