SCHEMBL2982997

SCHEMBL2982997

OC(Cl)(Cl)C1C2CC3CC(C2)CC1C3

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.41
EPHX2 P34913 1/20 0.32
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6456147 0.72 CYP2C9 (0.41) CYP2C9EPHX2HSD11B1
SCHEMBL4412291 0.71 CYP2C9 (0.45) CYP2C9EPHX2HSD11B1
SCHEMBL26709231 0.69 CYP2C9 (0.38) CYP2C9EPHX2HSD11B1
SCHEMBL10239375 0.69 CYP2C9 (0.38) CYP2C9EPHX2
SCHEMBL2190383 0.67 EPHX2 (0.39) CYP2C9EPHX2HSD11B1
SCHEMBL6346244 0.67 CYP2C9 (0.36) CYP2C9EPHX2HSD11B1
SCHEMBL12193712 0.65 CYP2C9 (0.35) CYP2C9EPHX2
SCHEMBL4067305 0.65 CYP2C9 (0.38) CYP2C9EPHX2
Adamantane SCHEMBL31336320 0.62 CYP2C9 (0.43) CYP2C9EPHX2
SCHEMBL3282039 0.61 CYP2C9 (0.35) CYP2C9EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776510-B2 Comprising base component which exhibits changed solubility in an alkali developing solution under action of acid and an acid-generator component which generates acid upon irradiation TOKYO OHKA KOGYO CO., LTD. (JP) 2010-08-17 US disclosed
US-20080311522-A1 Comprising base component which exhibits changed solubility in an alkali developing solution under action of acid and an acid-generator component which generates acid upon irradiation TOKYO OHKA KOGYO CO., LTD. (JP) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311522-A1 Comprising base component which exhibits changed solubility in an alkali developing solution under action of acid and an acid-generator component which generates acid upon irradiation GNG2, ACAD9, SCO2 CYP2C9 144/4885EPHX2 176/4885HSD11B1 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.