Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263090 | 0.92 | CYP3A4 (0.47) | — | |
| SCHEMBL13624787 | 0.92 | CYP3A4 (0.47) | — | |
| SCHEMBL4925753 | 0.92 | CYP3A4 (0.47) | — | |
| SCHEMBL12105567 | 0.91 | CFD (0.46) | CFD | |
| SCHEMBL3489676 | 0.91 | CYP3A4 (0.45) | — | |
| SCHEMBL13474429 | 0.91 | CYP3A4 (0.45) | — | |
| SCHEMBL16744019 | 0.90 | — | — | |
| SCHEMBL12765136 | 0.90 | CFD (0.41) | CFD | |
| SCHEMBL12108551 | 0.90 | CFD (0.45) | CFD | |
| SCHEMBL6886605 | 0.90 | CFD (0.47) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781474-B2 | Inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781474-B2 | Inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781474-B2 | Inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20100209391-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100209391-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20080019942-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080019942-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080019942-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC (US) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209391-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, HDGF | CFD 1348/4885 |
| US-20080019942-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, GTF3C3 | CFD 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.