Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662738 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL19662741 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL16415479 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL20883051 | 0.88 | KMT2A (0.39) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL15726196 | 0.87 | TSHR (0.46) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL15726193 | 0.87 | TSHR (0.46) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL2144069 | 0.84 | ALDH1A1 (0.44) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL2144064 | 0.84 | ALDH1A1 (0.44) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL5419125 | 0.84 | ALDH1A1 (0.44) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 | |
| SCHEMBL5415989 | 0.84 | ALDH1A1 (0.44) | L3MBTL1TSHRKMT2AALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153646-B | Pyridine dicarboxamide derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2022-08-02 | — | — | CN | disclosed |