Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.66 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.66 |
| ▸ | CTSD | P07339 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 1/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895758 | 0.92 | NPY4R (0.65) | BACE1BACE2CTSDOPRM1OPRD1 | |
| SCHEMBL29531717 | 0.92 | BACE1 (0.56) | BACE1BACE2CTSDOPRM1OPRD1 | |
| SCHEMBL29818222 | 0.90 | BACE1 (0.59) | BACE1BACE2CTSD | |
| SCHEMBL30659062 | 0.88 | BACE1 (0.75) | BACE1BACE2CTSD | |
| SCHEMBL30844216 | 0.88 | NPY4R (0.67) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL2184730 | 0.88 | NPY4R (0.64) | BACE1BACE2NPY1RNPY2RNPY4R | |
| SCHEMBL34471860 | 0.88 | BACE1 (0.67) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL29425531 | 0.87 | BACE1 (0.64) | BACE1BACE2CTSD | |
| SCHEMBL30725665 | 0.87 | BACE1 (0.54) | BACE1BACE2OPRM1OPRD1 | |
| SCHEMBL30799520 | 0.86 | BACE1 (0.61) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794879-B | Synthesis and application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | claimed |
| CN-112812152-B | Synthesis and anti-inflammatory application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | claimed |
| CN-112794879-B | Synthesis and application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112794879-B | Synthesis and application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112794879-B | Synthesis and application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112812152-B | Synthesis and anti-inflammatory application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112812152-B | Synthesis and anti-inflammatory application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112812152-B | Synthesis and anti-inflammatory application of Glu-Leu-Phe-Tyr-Val pentapeptide | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |