Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922349 | 1.00 | GFER (0.64) | GFERALDH1A1KDM4ETAAR1GAA | |
| SCHEMBL26922711 | 0.86 | KDM4E (0.67) | GFERALDH1A1KDM4ETAAR1GAA | |
| SCHEMBL29834783 | 0.86 | GFER (0.67) | GFERALDH1A1KDM4ETAAR1SMN1; SMN2 | |
| SCHEMBL26921832 | 0.86 | GFER (0.67) | GFERALDH1A1KDM4ETAAR1SMN1; SMN2 | |
| SCHEMBL29834840 | 0.84 | DRD2 (0.59) | GFERKDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL26922301 | 0.84 | DRD2 (0.59) | GFERKDM4EGAAHSD17B10L3MBTL1 | |
| Morinamide SCHEMBL563960 | 0.83 | GFER (0.67) | GFERALDH1A1KDM4ETAAR1L3MBTL1 | |
| Morinamide SCHEMBL29464523 | 0.83 | GFER (0.67) | GFERALDH1A1KDM4ETAAR1L3MBTL1 | |
| SCHEMBL26922276 | 0.83 | GFER (0.64) | GFERALDH1A1KDM4ETAAR1SMN1; SMN2 | |
| Morinamide SCHEMBL1650433 | 0.82 | GFER (0.66) | GFERALDH1A1KDM4ETAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288539-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH DUX4 OVEREXPRESSION | Research Institute at Nationwide Children's Hospital (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022169922-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH DUX4 OVEREXPRESSION | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-08-11 | — | — | WO | disclosed |