Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18718150 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2CNR2CNR1KDM4EPOLB | |
| SCHEMBL18718147 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL19451723 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL28820595 | 0.83 | CNR1 (0.65) | CNR2CNR1KDM4E | |
| SCHEMBL4754841 | 0.83 | KDM4E (0.50) | CNR2CNR1KDM4EPOLBMAPT | |
| SCHEMBL6188814 | 0.83 | MAPT (0.52) | SMN1; SMN2POLBALDH1A1TDP1RAB9A | |
| SCHEMBL16270143 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2CNR2CNR1KDM4EPOLB | |
| SCHEMBL2519952 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL19617291 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL1566850 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2CNR2CNR1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052880-A | Macrocyclic compounds | 芝诺管理公司 | 2022-09-13 | — | — | CN | disclosed |