Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101265 | 0.85 | MEN1 (0.71) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20521768 | 0.85 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL30834236 | 0.77 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL27201550 | 0.77 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6021703 | 0.75 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL13463408 | 0.74 | CYP3A4 (0.58) | NPC1RAB9AMAPTALDH1A1CYP3A4 | |
| SCHEMBL30449275 | 0.74 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL17962324 | 0.73 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20521838 | 0.72 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20521639 | 0.72 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052880-A | Macrocyclic compounds | 芝诺管理公司 | 2022-09-13 | — | — | CN | disclosed |