Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27201550 | 1.00 | NPC1 (0.46) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL20392685 | 0.84 | DYRK1A (0.43) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30877088 | 0.82 | LPL (0.36) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9985572 | 0.80 | MEN1 (0.60) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL25179630 | 0.78 | DGAT1 (0.46) | NPC1RAB9ADGAT1CSF1RSNCA | |
| SCHEMBL29362049 | 0.78 | DGAT1 (0.46) | NPC1RAB9ADGAT1CSF1RSNCA | |
| SCHEMBL20521768 | 0.77 | NPC1 (0.54) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL29834895 | 0.77 | NPC1 (0.54) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL1516719 | 0.77 | EGFR (0.48) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL189658 | 0.77 | DGAT1 (0.40) | NPC1RAB9AMEN1KMT2ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | disclosed |