SCHEMBL2983503

SCHEMBL2983503

CCNC(C)C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
ADRA2C P18825 1/20 0.31
HTR2A P28223 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
DRD3 P35462 1/20 0.31
OPRK1 P41145 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14157902 0.73 LMNA (0.38) SIGMAR1LMNASLC6A4ADRA1A
SCHEMBL15745624 0.72
SCHEMBL16748081 0.72
SCHEMBL22037300 0.72
SCHEMBL24875993 0.69
SCHEMBL15355775 0.69
SCHEMBL30122026 0.69
SCHEMBL20833383 0.68 SIGMAR1 (0.31) SIGMAR1LMNAMAPTADRA2CHTR2A
SCHEMBL23613203 0.68 SIGMAR1 (0.31) SIGMAR1LMNAMAPTADRA2CHTR2A
SCHEMBL13082857 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172369-B1 Synthesis of 2-deoxy-2-fluoro-arabinose derivates AIR PROD & CHEM (US) 2010-09-22 EP claimed
EP-1449839-B1 Fluorinated acrylic compounds, methods for preparation of the compounds and photoresist compositions containing same AIR PROD & CHEM (US) 2005-08-31 EP claimed