Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599491 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9ASRD5A1SRD5A2 | |
| Hydrochloric Acid SCHEMBL29600401 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9ASRD5A1SRD5A2 | |
| SCHEMBL29836682 | 0.83 | HSD17B3 (0.40) | ALDH1A1TSHR | |
| SCHEMBL4589714 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTSRD5A1SRD5A2TDP1 | |
| SCHEMBL9995642 | 0.73 | DRD2 (0.35) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| Hydrochloric Acid SCHEMBL3142402 | 0.72 | MAPT (0.50) | ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL29520814 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPTRAB9ASRD5A1 | |
| SCHEMBL27779069 | 0.72 | ALDH1A1 (0.32) | ALDH1A1SRD5A1SRD5A2 | |
| Hydrochloric Acid SCHEMBL27447092 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTSRD5A1SRD5A2TDP1 | |
| SCHEMBL27356467 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTSRD5A1SRD5A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037768-A1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-08-10 | — | — | EP | disclosed |