Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 14/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415975 | 1.00 | SERPINE1 (0.63) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL416780 | 0.88 | SERPINE1 (0.49) | SERPINE1 | |
| SCHEMBL421010 | 0.78 | SERPINE1 (1.00) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL540040 | 0.78 | IKBKE (0.39) | SERPINE1CA1CA2 | |
| SCHEMBL6358123 | 0.75 | SERPINE1 (0.89) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL6349535 | 0.75 | SERPINE1 (0.74) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL6351321 | 0.75 | SERPINE1 (0.89) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL420923 | 0.74 | SERPINE1 (0.61) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL20898592 | 0.74 | RAB9A (0.55) | — | |
| SCHEMBL420951 | 0.73 | IKBKE (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039276-A1 | INHIBITOR AGAINST EXPRESSION OF IMMUNE CHECKPOINT MOLECULE | Renascience Inc. (JP) | 2022-08-10 | — | — | EP | disclosed |