Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838632 | 0.78 | SERPINE1 (0.63) | SERPINE1CA1CA2 | |
| SCHEMBL415975 | 0.78 | SERPINE1 (0.63) | SERPINE1CA1CA2 | |
| SCHEMBL420951 | 0.73 | IKBKE (0.44) | IKBKETBK1SRD5A2FABP7ALDH1A1 | |
| SCHEMBL8651066 | 0.68 | KMT2A (0.56) | IKBKETBK1FABP7ALDH1A1FABP5 | |
| SCHEMBL20499591 | 0.67 | MAPT (0.47) | SRD5A2FABP7ALDH1A1CA1CA2 | |
| SCHEMBL15505016 | 0.66 | SMN1; SMN2 (0.44) | IKBKETBK1FABP7PIK3CDPIK3CA | |
| SCHEMBL31705648 | 0.65 | FABP7 (0.53) | IKBKETBK1FABP7ALDH1A1PIK3CD | |
| SCHEMBL3107969 | 0.65 | FABP7 (0.53) | IKBKETBK1FABP7ALDH1A1PIK3CD | |
| SCHEMBL20898592 | 0.64 | RAB9A (0.55) | TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26560458 | 0.63 | HTR1D (0.43) | IKBKETBK1FABP7PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415755-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Renascience CO., LTD. (JP) | 2012-02-08 | — | — | EP | disclosed |