Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186813 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL439092 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL407540 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL31407451 | 1.00 | ADRA2A (0.60) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| Hydrochloric Acid SCHEMBL783118 | 0.98 | ADRA2A (0.58) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| Bromide SCHEMBL11489853 | 0.98 | ADRA2A (0.58) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL406531 | 0.85 | HTT (0.61) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| Hydrochloric Acid SCHEMBL8179101 | 0.83 | HTT (0.59) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL568115 | 0.80 | ADRA2A (0.60) | ADRA2AADRA1AHTR1ADRD1TBXA2R | |
| SCHEMBL11484814 | 0.80 | ADRA2A (0.56) | ADRA2AADRA1AHTR1ADRD1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355303-A | Compounds and their use for the treatment of neurodegenerative, degenerative and metabolic disorders | 佛罗里达大学研究基金会公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-4284372-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | University of Florida Research Foundation, Incorporated (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165173-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-08-04 | — | — | WO | disclosed |