SCHEMBL29844652

SCHEMBL29844652

O=S1(=O)c2ccccc2Cc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.54
GPR3 P46089 1/20 0.52
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
NOX1 Q9Y5S8 1/20 0.46
CYP1A2 P05177 1/20 0.42
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
DRD4 P21917 1/20 0.39
DRD5 P21918 1/20 0.39
DRD3 P35462 1/20 0.39
MAOB P27338 1/20 0.39
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA4 P22748 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290638 1.00 MAOA (0.54) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL29958223 1.00 MAOA (0.54) MAOAGPR3KMT2AMEN1NOX1
Water SCHEMBL7420168 0.97 MAOA (0.53) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL9781138 0.89 MAOA (0.47) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL19820978 0.84 GPR3 (0.52) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL1501789 0.83 MAOA (0.42) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL18631368 0.82 MAOA (0.54) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL4732207 0.82 MAOA (0.54) MAOAGPR3KMT2AMEN1NOX1
Fluorene SCHEMBL25386791 0.81 GPR3 (0.70) MAOAGPR3KMT2AMEN1NOX1
SCHEMBL10197078 0.81 MAOA (0.41) MAOAGPR3KMT2AMEN1NOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687869-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS Immunic AG (DE) 2026-02-11 EP disclosed
WO-2024200872-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS IMMUNIC AG (DE) 2024-10-03 WO disclosed
CN-113429559-B Six-arm polyethylene glycol derivative with terminal iso-functionalization and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2024-08-23 CN disclosed
CN-112694608-B Six-arm polyethylene glycol derivative, preparation method and modified biological related substance 厦门赛诺邦格生物科技股份有限公司 2024-07-02 CN disclosed
CN-115010915-B Nitrogen-branched nine-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance thereof 厦门赛诺邦格生物科技股份有限公司 2024-06-11 CN disclosed
CN-116896918-A Organic semiconductor device 株式会社半导体能源研究所 2023-10-17 CN disclosed
CN-115010915-A Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative 厦门赛诺邦格生物科技股份有限公司 2022-09-06 CN disclosed
CN-110591079-B Preparation method of monofunctional nonlinear polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2022-08-02 CN disclosed