Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21680877 | 0.86 | NQO2 (0.57) | NQO2MTNR1ATDP1LMNAIDO1 | |
| SCHEMBL29845423 | 0.85 | NQO2 (0.61) | NQO2MTNR1ALMNAIDO1MEN1 | |
| SCHEMBL4597216 | 0.85 | NQO2 (0.60) | NQO2TDP1LMNAIDO1MEN1 | |
| SCHEMBL1579453 | 0.85 | NQO2 (0.75) | NQO2MTNR1AMTNR1B | |
| SCHEMBL4598153 | 0.84 | NQO2 (0.56) | NQO2TDP1LMNAIDO1MEN1 | |
| SCHEMBL20562323 | 0.81 | MTNR1A (0.51) | NQO2MTNR1ALMNAMEN1KMT2A | |
| SCHEMBL29844938 | 0.81 | NQO2 (0.59) | NQO2MTNR1ATDP1LMNAIDO1 | |
| SCHEMBL21614210 | 0.80 | NQO2 (0.54) | NQO2MTNR1AIDO1MTNR1BNAMPT | |
| SCHEMBL5467303 | 0.79 | NQO2 (0.54) | NQO2LMNAIDO1MEN1TSHR | |
| SCHEMBL6681403 | 0.78 | NQO2 (0.56) | NQO2TDP1LMNAIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446298-B2 | Pyrimidine derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11446298-B2 | Pyrimidine derivatives | PTGER1, PTGER4, PTGER2 | NQO2 1000/4885MTNR1A 447/4885TDP1 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.