Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21680877 | 0.87 | NQO2 (0.57) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL4598153 | 0.85 | NQO2 (0.56) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL29844950 | 0.85 | NQO2 (0.62) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL4381773 | 0.81 | NQO2 (0.61) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL4597984 | 0.81 | LMNA (0.47) | LMNAMEN1KMT2AHPGDMAPT | |
| SCHEMBL25734959 | 0.80 | MTNR1A (0.53) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL6681403 | 0.80 | NQO2 (0.56) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL3060044 | 0.79 | MTNR1A (0.55) | NQO2LMNAMEN1TSHRKMT2A | |
| SCHEMBL27399235 | 0.79 | NQO2 (0.49) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL21614210 | 0.79 | NQO2 (0.54) | NQO2IDO1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |