SCHEMBL29846496 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	3/20	0.45

▸	CNR1	P21554	1/20	0.43

▸	GAA	P10253	1/20	0.40

▸	KLKB1	P03952	1/20	0.40

▸	EZH2	Q15910	1/20	0.39

▸	PTPN7	P35236	1/20	0.39

▸	BRD4	O60885	1/20	0.39

▸	TPSAB1	Q15661	1/20	0.38

▸	BCHE	P06276	1/20	0.37

▸	ACHE	P22303	1/20	0.37

▸	PDE10A	Q9Y233	1/20	0.37

▸	HTR4	Q13639	1/20	0.36

▸	NTRK1	P04629	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29846595	0.91	EZH2 (0.49)	LMNACNR1EZH2
SCHEMBL29846578	0.88	BCHE (0.49)	LMNACNR1KLKB1PTPN7BRD4
SCHEMBL29846830	0.83	HTR4 (0.54)	HTR4
SCHEMBL29846604	0.82	EZH2 (0.51)	EZH2HTR4
SCHEMBL29846797	0.81	HDAC3 (0.41)	LMNACNR1BRD4BCHEACHE
SCHEMBL29846735	0.78	PPARG (0.48)	LMNA
SCHEMBL29846819	0.78	ALDH1A1 (0.50)	LMNAGAAHTR4
SCHEMBL29846668	0.78	KLKB1 (0.42)	GAAKLKB1BRD4
SCHEMBL29846644	0.77	KLKB1 (0.42)	LMNAKLKB1
SCHEMBL29846439	0.77	SMN1; SMN2 (0.37)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022123530-A1	BORONIC ACID COMPOUND	주식회사 엘지화학	2022-06-16	—	—	WO	disclosed