Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CDK4 | P11802 | 6/20 | 0.47 |
| ▸ | CCND1 | P24385 | 6/20 | 0.47 |
| ▸ | CDK1 | P06493 | 4/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.43 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514869 | 1.00 | CDK2 (0.47) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL29847920 | 0.91 | JUN (0.48) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL16823087 | 0.91 | JUN (0.48) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL16514537 | 0.91 | MYLK4 (0.44) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL29847614 | 0.91 | MYLK4 (0.44) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL16514044 | 0.89 | JAK2 (0.51) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL29847745 | 0.89 | JAK2 (0.51) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL29846996 | 0.89 | CDK4 (0.48) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL16514858 | 0.89 | CDK4 (0.48) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL29847842 | 0.87 | CDK4 (0.49) | CDK2CDK4CCND1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |