Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 5/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CCND1 | P24385 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CCND2 | P30279 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823087 | 1.00 | JUN (0.48) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL16822852 | 0.91 | FGFR2 (0.42) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL29847963 | 0.91 | FGFR2 (0.42) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL16514869 | 0.91 | CDK2 (0.47) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL29847537 | 0.91 | CDK2 (0.47) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL16823029 | 0.89 | JUN (0.49) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL16514481 | 0.89 | MAPK10 (0.55) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL16823164 | 0.89 | MAPK10 (0.49) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL28388525 | 0.87 | TTK (0.47) | JUNMAPK8MAPK10TTKCDK4 | |
| SCHEMBL16514357 | 0.87 | MAPK10 (0.57) | JUNMAPK8MAPK10TTKCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |