Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 5/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514114 | 1.00 | BACE1 (0.47) | BACE1SRCJAK2AXLAIMP2 | |
| SCHEMBL16823084 | 0.91 | AIMP2 (0.48) | BACE1SRCAXLAIMP2SYK | |
| SCHEMBL29847783 | 0.91 | AIMP2 (0.48) | BACE1SRCAXLAIMP2SYK | |
| SCHEMBL16515085 | 0.90 | JAK2 (0.44) | SRCJAK2AXLSYKPLK4 | |
| SCHEMBL29848007 | 0.90 | JAK2 (0.44) | SRCJAK2AXLSYKPLK4 | |
| SCHEMBL16513622 | 0.89 | SRC (0.49) | BACE1SRCJAK2AXLAIMP2 | |
| SCHEMBL29847543 | 0.89 | BACE1 (0.48) | BACE1SRCJAK2AXLAIMP2 | |
| SCHEMBL16513888 | 0.89 | BACE1 (0.48) | BACE1SRCJAK2AXLAIMP2 | |
| SCHEMBL16515429 | 0.89 | BACE1 (0.48) | BACE1SRCJAK2AXLAIMP2 | |
| SCHEMBL16823029 | 0.87 | JUN (0.49) | BACE1SRCJAK2SYKPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |