Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514429 | 1.00 | BRAF (0.41) | BRAFNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL29847627 | 0.94 | BRAF (0.41) | BRAFNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL16515043 | 0.94 | BRAF (0.41) | BRAFNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL16515095 | 0.92 | SYK (0.46) | NPC1RAB9ASMN1; SMN2EGFRERBB3 | |
| SCHEMBL29847847 | 0.92 | SYK (0.46) | NPC1RAB9ASMN1; SMN2EGFRERBB3 | |
| SCHEMBL16514101 | 0.91 | MYLK4 (0.43) | EGFRCSF1RLCKCDK2CDK4 | |
| SCHEMBL29847686 | 0.91 | MYLK4 (0.43) | EGFRCSF1RLCKCDK2CDK4 | |
| SCHEMBL29847540 | 0.89 | SYK (0.45) | BRAFNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL16514323 | 0.89 | SYK (0.45) | BRAFNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL16513785 | 0.89 | MAPK10 (0.45) | BRAFNPC1RAB9ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |