Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514000 | 1.00 | AIMP2 (0.40) | AIMP2FGFR2FGFR3MTORSMG1 | |
| SCHEMBL16515085 | 0.91 | JAK2 (0.44) | FGFR3CDK4CDK2GSK3BSRC | |
| SCHEMBL29848007 | 0.91 | JAK2 (0.44) | FGFR3CDK4CDK2GSK3BSRC | |
| SCHEMBL29847783 | 0.90 | AIMP2 (0.48) | AIMP2FGFR2FGFR3SRCBACE1 | |
| SCHEMBL16823084 | 0.90 | AIMP2 (0.48) | AIMP2FGFR2FGFR3SRCBACE1 | |
| SCHEMBL16514433 | 0.90 | AXL (0.38) | AIMP2FGFR2FGFR3MTORCDK4 | |
| SCHEMBL16513558 | 0.90 | AIMP2 (0.42) | AIMP2FGFR2FGFR3MTORSMG1 | |
| SCHEMBL16513725 | 0.88 | MTOR (0.41) | AIMP2FGFR2FGFR3MTORCDK4 | |
| SCHEMBL29847963 | 0.88 | FGFR2 (0.42) | AIMP2FGFR2FGFR3MTORSMG1 | |
| SCHEMBL16822852 | 0.88 | FGFR2 (0.42) | AIMP2FGFR2FGFR3MTORSMG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |