Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.41 |
| ▸ | JUN | P05412 | 5/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 4/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822852 | 1.00 | FGFR2 (0.42) | FGFR2FGFR3MTORSMG1MAPK10 | |
| SCHEMBL16823087 | 0.91 | JUN (0.48) | MAPK10JUNMAPK8TTKCDK4 | |
| SCHEMBL29847920 | 0.91 | JUN (0.48) | MAPK10JUNMAPK8TTKCDK4 | |
| SCHEMBL29847614 | 0.91 | MYLK4 (0.44) | ZAP70CDK4CDK2CSF1RKCNH2 | |
| SCHEMBL16514537 | 0.91 | MYLK4 (0.44) | ZAP70CDK4CDK2CSF1RKCNH2 | |
| SCHEMBL16823103 | 0.89 | ZAP70 (0.42) | FGFR2FGFR3MTORSMG1TTK | |
| SCHEMBL16514757 | 0.89 | MAPK10 (0.47) | FGFR2FGFR3MTORSMG1MAPK10 | |
| SCHEMBL29847827 | 0.89 | AIMP2 (0.46) | FGFR2FGFR3MTORSMG1MAPK10 | |
| SCHEMBL16515205 | 0.89 | MAPK10 (0.42) | FGFR2FGFR3MAPK10JUNMAPK8 | |
| SCHEMBL16823092 | 0.89 | AIMP2 (0.46) | FGFR2FGFR3MTORSMG1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |