Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515095 | 1.00 | SYK (0.46) | SYKCDK2CDK1CDK4CCNB1 | |
| SCHEMBL16823185 | 0.94 | SYK (0.46) | SYKCDK2CDK1CDK4CCNB1 | |
| SCHEMBL29847823 | 0.94 | SYK (0.46) | SYKCDK2CDK1CDK4CCNB1 | |
| SCHEMBL29847797 | 0.92 | BRAF (0.41) | SYKCDK2CDK4NPC1RAB9A | |
| SCHEMBL16514429 | 0.92 | BRAF (0.41) | SYKCDK2CDK4NPC1RAB9A | |
| SCHEMBL16514184 | 0.92 | CDK2 (0.46) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL29848066 | 0.92 | CDK2 (0.46) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL16515006 | 0.89 | SYK (0.47) | SYKCDK2CDK1CDK4CCNB1 | |
| SCHEMBL29848004 | 0.89 | SYK (0.47) | SYKCDK2CDK1CDK4CCNB1 | |
| SCHEMBL16513629 | 0.88 | JUN (0.51) | SYKCDK2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |