Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198746 | 0.81 | KDM4C (0.36) | ADRB2KDM4CALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30270070 | 0.78 | KDM4E (0.39) | ADRB2ALDH1A1TGFBR1OGAABL1 | |
| SCHEMBL29849864 | 0.78 | NR4A2 (0.33) | KDM4CNR4A2SOS2 | |
| SCHEMBL18839509 | 0.78 | NOS3 (0.36) | ADRB2TGFBR1OGAGAAABL1 | |
| SCHEMBL18839547 | 0.78 | KDM4E (0.39) | ADRB2ALDH1A1TGFBR1OGAABL1 | |
| SCHEMBL20909976 | 0.78 | UHRF1 (0.42) | ADRB2ALDH1A1MAPTOGAABL1 | |
| SCHEMBL20644586 | 0.75 | OGA (0.36) | ADRB2ALDH1A1PDK2TGFBR1OGA | |
| SCHEMBL31059829 | 0.75 | KDM4C (0.42) | KDM4CALDH1A1MAPTL3MBTL1NR4A2 | |
| SCHEMBL31059631 | 0.75 | KDM4C (0.42) | KDM4CALDH1A1MAPTL3MBTL1NR4A2 | |
| SCHEMBL31059613 | 0.75 | KDM4C (0.42) | KDM4CALDH1A1MAPTL3MBTL1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173849-A1 | (HETERO)ARYLAMINO-CYCLOHEXYL-SULFONYL DERIVATIVES AS CCR6 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-08-18 | — | — | WO | disclosed |