Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 6/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22425046 | 0.83 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL20644586 | 0.79 | OGA (0.36) | ADRB2ALDH1A1ABL1OGA | |
| SCHEMBL18839547 | 0.78 | KDM4E (0.39) | KDM4EADRB2ALDH1A1ABL1OGA | |
| SCHEMBL22010017 | 0.78 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL18839509 | 0.78 | NOS3 (0.36) | NOS3NOS2ADRB2ABL1OGA | |
| SCHEMBL30270070 | 0.78 | KDM4E (0.39) | KDM4EADRB2ALDH1A1ABL1OGA | |
| SCHEMBL29849938 | 0.78 | ADRB2 (0.35) | MAPTADRB2ALDH1A1ABL1OGA | |
| SCHEMBL643383 | 0.76 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL26916427 | 0.76 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KDM4E | |
| SCHEMBL11983491 | 0.74 | UHRF1 (0.50) | UHRF1CCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |