Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913867 | 0.95 | ECE1 (0.36) | MMEECE1ITGB2ICAM1ITGAL | |
| SCHEMBL5318838 | 0.93 | UTS2R (0.32) | MMEECE1 | |
| SCHEMBL5318831 | 0.93 | UTS2R (0.32) | MMEECE1 | |
| SCHEMBL29461516 | 0.92 | MME (0.44) | MME | |
| SCHEMBL29708173 | 0.91 | MME (0.46) | MMEECE1 | |
| SCHEMBL29630501 | 0.91 | BACE1 (0.34) | MMEECE1BACE1 | |
| SCHEMBL29373629 | 0.89 | ECE1 (0.39) | MMEECE1ITGB2ICAM1ITGAL | |
| SCHEMBL30209180 | 0.89 | PDCD1LG2 (0.36) | MMEECE1ITGB2ICAM1ITGAL | |
| SCHEMBL31229006 | 0.88 | ACE (0.38) | MME | |
| SCHEMBL5318834 | 0.88 | MME (0.35) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037715-A1 | PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF | Beijing Xuanyi Pharmasciences Co., Ltd. (CN) | 2022-08-10 | — | — | EP | disclosed |