SCHEMBL29913867

SCHEMBL29913867

NC(=O)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 3/20 0.36
▸ MME P08473 2/20 0.35
▸ ITGB2 P05107 1/20 0.34
▸ ICAM1 P05362 1/20 0.34
▸ ITGAL P20701 1/20 0.34
▸ CA2 P00918 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ PDCD1LG2 Q9BQ51 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ BACE1 P56817 2/20 0.32
▸ KISS1R Q969F8 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630501 0.96 BACE1 (0.34) ECE1MMEPDCD1LG2CD274BACE1
SCHEMBL29851664 0.95 MME (0.38) ECE1MMEITGB2ICAM1ITGAL
SCHEMBL29373629 0.94 ECE1 (0.39) ECE1MMEITGB2ICAM1ITGAL
SCHEMBL30209180 0.94 PDCD1LG2 (0.36) ECE1MMEITGB2ICAM1ITGAL
SCHEMBL30038078 0.92 MME (0.39) ECE1MMECA2CA1
SCHEMBL31707374 0.91 MME (0.38) ECE1MMEITGB2ICAM1ITGAL
SCHEMBL29447737 0.91 MME (0.36) ECE1MMEBACE1
SCHEMBL30192164 0.91 BACE1 (0.36) ECE1MMEITGB2ICAM1ITGAL
SCHEMBL29560167 0.91 MME (0.36) MME
SCHEMBL29376470 0.90 MME (0.36) MMEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144860-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2026-05-28 — — US disclosed
US-12458691-B2 HIV-1 ENV fusion peptide immunogens and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-11-04 — — US disclosed
US-20230338507-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-26 — — US disclosed
US-11602559-B2 HIV-1 Env fusion peptide immunogens and their use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-03-14 — — US disclosed
EP-4070815-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) 2022-10-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338507-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE CD4, LY96, ICOS ECE1 194/4885MME 92/4885ITGB2 4067/4885
US-20260144860-A1 HIV-1 ENV FUSION PEPTIDE IMMUNOGENS AND THEIR USE CD4, TIMCC, CD81 ECE1 2749/4885MME 3828/4885ITGB2 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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