Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPRA | P18433 | 1/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318838 | 0.93 | UTS2R (0.32) | MME | |
| SCHEMBL5318831 | 0.93 | UTS2R (0.32) | MME | |
| SCHEMBL29851664 | 0.88 | MME (0.38) | MME | |
| SCHEMBL30038078 | 0.87 | MME (0.39) | MME | |
| SCHEMBL29461516 | 0.87 | MME (0.44) | MME | |
| SCHEMBL29761682 | 0.86 | MME (0.43) | MME | |
| SCHEMBL29598237 | 0.85 | MME (0.40) | MME | |
| SCHEMBL24525829 | 0.85 | ERAP2 (0.35) | MME | |
| SCHEMBL31229006 | 0.84 | ACE (0.38) | MME | |
| SCHEMBL1371052 | 0.84 | OPRD1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095583-A2 | METHODS FOR TREATING CANCER AND SENSITIZING CANCER CELLS USING THE SERINE PROTEASE INHIBITOR, MASPIN | CHILDREN'S MEMORIAL RESEARCH CENTER (US) | 2007-08-23 | — | — | WO | disclosed |
| EP-1805219-A1 | ANGIOPOIETIN-2 SPECIFIC BINDING AGENTS | Amgen, Inc (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045049-A1 | ANGIOPOIETIN-2 SPECIFIC BINDING AGENTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |